Advances in Gastroenterology, Hepatology & Endoscopy

Stem Cells

Gastric stem cells represent an adult stem cell population residing in the stomach tissues with high proliferative potential, which enables efficient stomach epithelium regeneration and repair. Following the comprehensive investigation of intestinal stems cells, the identity of gastric stem cells is being explored. In comparison with intestinal stems cells, gastric stem cells share many properties, but they differ in fundamental aspects regarding location, molecular cell markers and their specific growth niches. The mucosa in all parts of the human stomach is lined by a simple columnar epithelium that has numerous tubular invaginations in its lamina  propria.

Stem cells are present inside different types of tissue. Scientists have found stem cells in tissues, including:

• The brain


• Bone marrow


• Blood and blood vessels


• Skeletal muscles


• Skin


• The liver